Wednesday, June 16, 2010

CHANGE OF BLOOD IN BABY AND JAUNDICE..

A common condition in newborns, jaundice refers to the yellow color of the skin and whites of the eyes caused by excess bilirubin in the blood. Bilirubin is produced by the normal breakdown of red blood cells.
Normally, bilirubin passes through the liver and is excreted as bile through the intestines. Jaundice occurs when bilirubin builds up faster than a newborn's liver can break it down and pass it from the body. Reasons for this include:


  • Newborns make more bilirubin than adults do since they have more turnover of red blood cells.the heamoglobin(functional unit in red blood cell) of fetal is Hbf.Hbf contain 2 alpha globulin and 2 gamma globulin.gamma globulin special for fetal to take oxygen from the mother blood and bind oxygen more tightly.gamma globulin is only normal in fetal but abnormal present in adult.so, the great turnover of blood occur in the  body to change gamma globulin to beta globulin usually for adult.
  • A newborn baby's still-developing liver may not yet be able to remove adequate bilirubin from the blood.
  • Too large an amount of bilirubin is reabsorbed from the intestines before the baby gets rid of it in the stool.
High levels of bilirubin — usually above 25 mg — can cause deafness, cerebral palsy, or other forms of brain damage in some babies. In less common cases, jaundice may indicate the presence of another condition, such as an infection or a thyroid problem. The American Academy of Pediatrics (AAP) recommends that all infants should be examined for jaundice within a few days of birth.

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